Head of Laboratory
Mironova Galina Dmitrievna
d.b.s., prof., HSW of RF
(4967) 73-09-59
(4967) 73-92-65
(495) 623-74-67 (доб. 2-62)
The main line of work of the Laboratory is the research into the structure and regulation mechanisms of the mitochondrial ATP-dependent potassium channel (mitoKATP) and fatty acid/calcium-induced pore, as well as the role of these transport systems in forming the mechanisms of adaptation of the organism to hypoxia.
The structure and electrophysiological properties of the mitoKATP are studied, as well as its functional relationships to intermediate filament proteins.
Methods
Isolation and purification of membrane channel proteins; incorporation of the proteins into the bilayer lipid membrane and determination of their electrophysiological characteristics; mitochondrial respiration; simultaneous registration of ion fluxes and membrane potential; immunoelectron microscopy; methods of research into the properties of artificial membranes.
