1. Research into the cellular and molecular mechanisms of calcinosis; development of technologies for production of biomaterials with high regenerative potential for traumatology/orthopedics, dentofacial, cardiovascular and plastic surgery.
2. Research into the regulation of mitochondrial and cellular functions with participation of nucleotide-binding proteins of the outer membrane and intermembrane space of mitochondria.
3. Development of biomimetics of tissues, organs and systems of organs in vitro.
4. Development of target substances selectively causing death of cancer cells.
Cultivation of cells, unique methods of perfusion/diffusion cultivation to create tissue-like models of organs and tissues in vitro; models of hetero- and orthotopic implantation of materials; methods of tissue engineering, biodegradable polymers; methods of preparative biochemistry and molecular biology; differential histological and immunohistological analyses and bioimaging; spectrofluorimetry; methods of multiparameter (high-throughput/high-content) analysis of the effect of substances and materials in vitro; vital and confocal microscopies.